AANEM News Express Related to  NSEB

AANEM News Express

Science News: Physiological Localization by Sensory and Motor Inching Studies and Structural Abnormalities Detected by Ultrasonographic Changes in Carpal Tunnel Syndrome

This is a cross-sectional study that investigated carpal tunnel syndrome (CTS) to determine correlation of electrophysiologically localized entrapment site using inching study with anatomic entrapment site identified by ultrasound (US).

Science News: Decrease in Serum Anti-MAG Autoantibodies Is Associated With Therapy Response in Patients With Anti-MAG Neuropathy: Retrospective Study

This retrospective analysis tested the hypothesis that changes in serum anti-myelin-associated glycoprotein (MAG) autoantibodies are associated with clinical response to immunotherapy in patients with anti-MAG neuropathy. The study evaluated relative change in anti-MAG immunoglobulin M (IgM) titers, paraprotein level or total IgM, before, during or post treatment.

Science News: Electrophysiological Study of the Tibial Nerve Across the Tarsal Tunnel in Distal Symmetric Diabetic Polyneuropathy

In this study, 124 consecutive patients with distal symmetric diabetic polyneuropathy diagnosed using the diabetic neuropathic index (DNI) were prospectively enrolled to investigate abnormalities of motor conduction in the tibial nerve across the tarsal tunnel.

Science News: Guillain-Barré Syndrome Following COVID-19 Vaccines: A Scoping Review

The association of Guillain-Barré syndrome (GBS) with COVID-19 vaccines has been unclear.
As part of postauthorization safety surveillance, the US Food and Drug Administration (FDA) has identified a potential safety concern for GBS following receipt of the COVID-19 vaccine.

Science News: Safety and Effectiveness of Long-term Intravenous Administration of Edaravone for Treatment of Patients With Amyotrophic Lateral Sclerosis

This study evaluates the long-term safety and effectiveness of intravenous edaravone therapy for patients with ALS in a real-world clinical setting.

Science News: Comorbidities in Older Patients With Myasthenia Gravis - Comparison Between Early- and Late-Onset Disease

Based on the age of onset, myasthenia gravis (MG) is differentiated into early-onset (EOMG) and late-onset (LOMG). This study’s aim was to investigate comorbidities in the older population and compare EOMG and LOMG patients. The age of 50 is used as the cutoff to differentiate EOMG and LOMG.

Science News: Utility of Shear Wave Elastography and High-Definition Color for Diagnosing Carpal Tunnel Syndrome

This prospective study investigated shear wave elastography and high definition color in carpal tunnel syndrome (CTS) patients with variable degrees of severity. The authors recruited patients with clinical evidence of CTS and healthy volunteers as a control group. The patients underwent EDX testing, and the severity of CTS was determined using Canterbury grading (6 grades). The patients were subsequently classified into nerve conduction study (NCS)-negative (normal NCS), mild-to-moderate CTS (grades 1–3), and severe CTS (grades 4–6).

Science News: Amyotrophic Lateral Sclerosis Mortality Rates in Latin America and the Caribbean: A Meta-Analysis

Heterogeneity of amyotrophic lateral sclerosis (ALS) epidemiology has been noted amongst geographic population. Previous studies have shown lower frequency of ALS amongst non Caucasian descents. Furthermore, interesting findings like lowest mortality from ALS in mixed ancestry has been noted. This study conducted a meta-analysis of population-based data to describe ALS mortality rates in Latin America.

Science News: A New Tool for Assessment of Motor Axon Excitability. A Multicenter Prospective Study

This study is a multicenter study that assessed a novel electrodiagnostic test, ‘iMAX’, to test the motor axon excitability. The study was performed in four centers in Belgium and France. The authors aimed to evaluate the test reliability and consistency among the four centers, provide normative values, and determine its ability to detect impaired motor axon excitability in patients with peripheral neuropathies. 

Science News: Dermatomyositis: Muscle Pathology According to Antibody Subtypes

Dermatoyositis (DM) is a rare disease that causes muscle weakness and skin rash. This study provides good evidence for a variety of DM subtypes and highlights the importance of looking at myxovirus resistant protein expression in muscle biopsies when evaluating inflammatory myopathies.