What is Mononeuritis Multiplex?

Mononeuritis multiplex, also known as mononeuropathy multiplex or multifocal neuropathy, is a type of peripheral neuropathy. It happens when there is damage to two or more different nerve areas. Mononeuritis multiplex is actually a group of symptoms rather than its own disease. Its symptoms include numbness, tingling, abnormal sensation, lack of sensation, difficulty to control movement, or an inability to move a part of the body.

Who gets Mononeuritis Multiplex?

Anyone can have mononeuritis multiplex, but people with diabetes mellitis or connective tissue diseases are more likely to get it. Another common cause includes a lack of oxygen caused by decreased blood flow. A common cause is from vasculitis. This is an inflammation around some blood vessels that can affect the vasa nervorum, or blood vessels around certain nerves. This can be seen in many disorders including: polyarteritis nodosa, rheumatoid arthritis, systemic lupus erythematosus, Wegener’s granulomatosis, and scleroderma.

How is Mononeuritis Multiplex diagnosed?

After learning the patient's history, a physician may perform nerve conduction velocity tests and EMG, or take a nerve biopsy.

How is Mononeuritis Multiplex treated?

The goal of treatment is to control the symptoms of mononeuritis multiplex. A physician may recommend physical therapy or orthopedic interventions. If the cause of mononeuritis multiplex can be identified and treated, a patient may be able to fully recover.

More Information

Foundation for Peripheral Neuropathy
American Chronic Pain Association

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