News Express

Science News: Improving Muscle Grade Accuracy With EMG

April 17, 2025

This review discusses a study that supports the reliability of MMT in assessment of key muscles in spinal cord injury patients.

Science News: Initial Clinical Experience and Outcomes of Ravulizumab in AChR+ gMG

April 03, 2025

Analyzing a study that evaluates the initial clinical experience of using ravulizumab, a long-acting C5 monoclonal antibody, in patients with acetylcholine receptor antibody-positive generalized myasthenia gravis (AChR+ gMG).

Science News: Long-Term Efficacy and Safety of Apitegromab in Nonambulatory SMA Patients

March 20, 2025

This study examines the long-term efficacy and safety of apitegromab (SRK-015) in nonambulatory patients with SMA over 36 months, showing sustained motor function improvements and a favorable safety profile.

Science News: Serial Nerve Conduction Studies in Guillain-Barré Syndrome: Its Usefulness and Precise Timing

March 11, 2025

This multicenter retrospective study aimed to assess the usefulness of serial nerve conduction studies in patients with Guillain-Barré syndrome who undergo nerve conduction studies at an early stage.

Science News: Optimization of Muscle Selection for Needle Electromyography in Isolated C6 Root Lesion: A Prospective Chart Review Study

February 25, 2025

The aim of the study was to evaluate muscles with more prominent needle electromyographic findings to optimize needle EMG screening of isolated C6 radiculopathy in patients with C6 root lesions.

Science News: Use of Baclofen as a Treatment for Nocturnal Calf Cramps in Individuals With Lumbar Spinal Stenosis: A Prospective Randomized Study

February 17, 2025

A group of 40 adults with spinal stenosis who complained of nocturnal calf cramps (NCCs) more than once a week were enrolled in a study to measure the use of baclofen as a treatment for NCCs.

Science News: A Study on the Epidemiology of COVID-19 Related Guillain-Barré Syndrome in the United States

January 30, 2025

Several neurological complications have been reported with COVID-19, including Guillain–Barré syndrome (GBS). Researchers looked at incidence, baseline characteristics, and in-hospital outcomes of COVID 19–associated GBS in the United States.

Science News: Musician’s Dystonia in a Percussionist - Clinical Video Analysis and Botulinum Toxin Intervention: A Case Report

January 17, 2025

This is a case of a 63 year old male percussionist with musician’s focal hand dystonia treated with botulinum toxin.

Science News: Rate and Characteristics of Inflammatory Neuropathies Associated With Brentuximab Vedotin Therapy

January 02, 2025

Brentuximab-induced neuropathy (BV-CN) can present as a mild sensory neuropathy or a severe inflammatory form (BV-IN) with significant motor impairment. BV-IN often requires treatment discontinuation and immunotherapy.

Science News: Physical Strain of Walking in People With Neuromuscular Diseases Is High and Relates To Step Activity in Daily Life

December 17, 2024

The study examined the physical strain of walking in individuals with neuromuscular disease (NMD) by measuring VO2walk and VO2peak. It also explored the relationship between daily step count, time in moderate-to-vigorous physical activity, and walking strain.

Science News: Living With Dysphagia: A Survey Exploring the Experiences of Adults Living With Neuromuscular Disease and Their Caregivers in the United Kingdom

December 06, 2024

This cross-sectional study used surveys to explore dysphagia experiences in neuromuscular disease.

Science News: Safety and Tolerability of Phenylbutyrate in Inclusion Body Myositis

November 20, 2024

This phase 1 pilot study showed that phenylbutyric acid (PBA) is safe and well-tolerated in treating inclusion body myositis (IBM). While limited by small sample size, the study found significant biomarker improvement, supporting further research on PBA's therapeutic potential.

Science News: Nerve Transfer After Cervical Spinal Cord Injury: Who Has a "Time Sensitive" Injury Based on Electrodiagnostic Findings?

November 11, 2024

The study at hand investigated the use of nerve conduction study (NCS) to investigate the degree of injury and change overtime to help identify the subpopulation of traumatic spinal cord injury tSCI that would best serve by early consideration of nerve transfer.

Science News: Long-Read Sequencing Improves Diagnostic Rate in Neuromuscular Disorders

October 28, 2024

Short read sequencing has limitations including inaccurate genome assembly, an inability to detect large structural variants and variants in hard to sequence areas, such as highly repetitive sequences.

Science News: Clinicopathologic Findings in Patients With Paraneoplastic Neuropathies and Antibodies Strongly Associated With Cancer

October 09, 2024

This is a retrospective review of the electronic medical record over a 27-year period of patients with paraneoplastic neurological syndromes (antibody positive) and clinicopathological findings on nerve biopsies.

Science News: Clinical Relevance of Distinguishing Autoimmune Nodopathies From CIDP: Longitudinal Assessment in a Large Cohort

September 30, 2024

This prospective study aimed to assess the treatment response in patients with autoimmune nodopathy (AN) initially diagnosed as chronic inflammatory demyelinating polyradiculoneuropathy (CIDP).

Science News: Dry Needling Versus Corticosteroid Injections To Treat Tendinopathy: A Systematic Review

September 12, 2024

This study is looking at the comparison of dry needling to steroid injection for treating tendinopathy.

Science News: Analysis of Predictive Factors for the Poor Prognosis of Peripheral Facial Paralysis

August 28, 2024

The aim of the study is to evaluate predictive factors for a poor prognosis in patients with facial paralysis evaluated in the rehabilitation department of a tertiary hospital.

Science News: Effectiveness of Pulse Electromagnetic Field Therapy in Patients With Subacromial Impingement Syndrome: A Double-Blind Randomized Sham-Controlled Study

August 19, 2024

The authors of this study investigated PEMF application in subacromial impingement syndrome (SIS) in conjunction with physical therapy.

Science News: Insights Into Refractory Chronic Inflammatory Demyelinating Polyneuropathy: A Comprehensive Real-World Study

August 01, 2024

In this study, the authors sought to delineate the clinical characteristics, disease progression patterns, and potential risk factors associated with refractory chronic inflammatory demyelinating polyneuropathy (CIDP), as well as the electrophysiological features of this condition.