AANEM Education News Express

AANEM News Express

Science News: Comparison Between Rituximab Treatment for New-Onset Generalized Myasthenia Gravis and Refractory Generalized Myasthenia Gravis

This was a retrospective cohort study conducted in a university hospital in Sweden to compare efficacy between rituximab and conventional immunosuppressants in the refractory and newly diagnosed generalized myasthenia gravis.

Science News: Which Ultrasound Parameter is More Accurate in the Diagnosis of Carpal Tunnel Syndrome

Ultrasound (US) can be useful to diagnosing carpal tunnel syndrome (CTS). Most US CTS studies have looked at median nerve cross sectional area (CSA). Others use resistive index (RI) or strain ratio (SR) as the criteria. This study compared CSA with RI and SR in CTS.

Science News: Peripheral Nerve Compression Syndromes in Children

Non-traumatic neuropathies of the upper limb are rare in children. Therefore, high quality evidence-based diagnostic guidelines are lacking.


Science News: Serum Neurofilament Light Chain Predicts Long-Term Prognosis in Guillain-Barré Syndrome Patients

This is presented by the International GBS Outcome Study (IGOS), based in Spain. The neurofilament light (NfL) chain is an increasingly studied biomarker for axonal injury, previously studied in GBS. This study evaluates it as a prognostic maker in GBS.

Latest Anthology of Articles from the News Science Editorial Board Now Available

The 2020 News Science Anthology is now available.

Science News: Retrospective Analysis of Eculizumab in Patients with Acetylcholine Receptor Antibody-Negative Myasthenia Gravis: A Case Series

Eculizumab has been approved and used for AChR antibody positive myasthenia gravis but little is known about its efficacy for AChR seronegative cases.

Science News: Placebo Effect in Chronic Inflammatory Demyelinating Polyneuropathy: The PATH Study and a Systematic Review

Placebos (pharmacologically inert preparations) are used in treatment trials to assess the true effect of trial medication. Placebo responses have been noted in CIDP trials including the most recent PATH trial investigating subcutaneous IVIG as maintenance therapy.

Science News: An Appraisal of Electrodiagnostic Studies in Stiff Person Syndrome

This is a review of electrodiagnostic (EDX) findings for diagnosis of stiff person syndrome (SPS). The authors performed a literature review of EDX findings in SPS as well as an online survey of SPS among EDX labs accredited by the AANEM.

Science News: Utility of Nerve Conduction Studies and Ultrasonography in Ulnar Neuropathies at the Elbow of Different Severity

This study compared ultrasound (US), short segment nerve conduction studies (SSNCS), and 10 cm NCS across the elbow, for detection and localization of Ulnar nerve compression at the elbow (UNE).

Science News: Neurologic Manifestations of Hospitalized Patients With Coronavirus Disease 2019 in Wuhan, China

This is a retrospective analysis of 214 patients from WUHAN, China with COVID-19, 126 patients (58.9%)non severe infection, and 88 patients (41.1%) had severe infection according to respiratory status.