AANEM Connect
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Small fiber neuropathy with MGUS
I have a patient with a small fiber neuropathy who started with constant severe burning pain in his feet. After 2 or 3 infusions of Rituximab his pain intensity is now 20% of the original intensity and his pain is no longer constant with the pain lasting from 2 or 3 hours a day up to 11 hours (2 or 3 hours the most common duration.
He has a sustained response to the Rituximab but seems to be hitting a plateau in terms of response. Would switching him to another agent possibly produce additional benefit? If not how long should I continue the Rituximab. He has had 3 infusions so far?
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