AANEM Connect

Hi, I have a few cases in which the EMG and NC is c/w axonal Neuropathy, but I or a different MD already have sent the ganglioside antibody panel. I have repeated the panel to make sure is not a lab error. I have a few patients testing positive for GQ1b, and GD1A antibodies, both with sensory and motor axonal neuropathies, some of them progressive in symptoms and sign,s which you would like to consider as Autoimmune Neuropathies that could benefit from IVIG or other treatments; yet is difficult to get them approved since they are not the typical CIDP. Although the literature mentions cases of axonal CIDP, or rare chronic cases of Miller Fisher Syndrome, I am not entirely sure what to do with those patients, since, yes, I would like at least a 6-month trial of IVIG to see if there is response or not. In same group of patients, there are some patient s with absent sensory and motor responses and the feet ( no surals, peroneal sensory, plantar and no peroneal or tibial CMAPS) with normal or reduced peroneal response at the TA but no significant active denervation in the leg which you would think are most likely related to proximal demyelination, but yet cannnot oficiallly call the EMG as CIDP. Have you encountered similar cases, and what would you advise? Thanks.