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hodgkin lymphoma and chemotherapy in a teenager
we realised an EMG to a 14 year old girl today, presented to the Electrodiagnostic unit for muscle weakness and fatigue, she has Hodgkin lymphoma who received a chemotherapy with this OEPA scheme ( Vincristine Sulfate, Etoposide Phosphate, Prednisone, Doxorubicin Hydrochloride) she is in the fifth session now; started from august,
In the EMG we found a pure diffuse motor neuropathy, and an ongoing denervation in the abductor policis previs and anterior tibialis with poor recruitment, and very prolonged F waves in lower limbs (60ms), my question is: is it only a neuropathy induced by chemotherapy, is it described in the literature? and why sensory fibers are spared in this case?
Can neurotoxicity affect motor fibers and not sensory fibers and vice versa?
Thank you so much
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