AANEM News Express Related to NSEB

Science News: Guillain-Barré Syndrome Following COVID-19 Vaccines: A Scoping Review

    8/4/2022
The association of Guillain-Barré syndrome (GBS) with COVID-19 vaccines has been unclear.
 
As part of postauthorization safety surveillance, the US Food and Drug Administration (FDA) has identified a potential safety concern for GBS following receipt of the COVID-19 vaccine.
 

Science News: Safety and Effectiveness of Long-term Intravenous Administration of Edaravone for Treatment of Patients With Amyotrophic Lateral Sclerosis

    8/4/2022
This study evaluates the long-term safety and effectiveness of intravenous edaravone therapy for patients with ALS in a real-world clinical setting.

Science News: Comorbidities in Older Patients With Myasthenia Gravis - Comparison Between Early- and Late-Onset Disease

    7/22/2022
Based on the age of onset, myasthenia gravis (MG) is differentiated into early-onset (EOMG) and late-onset (LOMG). This study’s aim was to investigate comorbidities in the older population and compare EOMG and LOMG patients. The age of 50 is used as the cutoff to differentiate EOMG and LOMG.
 

Science News: Utility of Shear Wave Elastography and High-Definition Color for Diagnosing Carpal Tunnel Syndrome

    7/22/2022
This prospective study investigated shear wave elastography and high definition color in carpal tunnel syndrome (CTS) patients with variable degrees of severity. The authors recruited patients with clinical evidence of CTS and healthy volunteers as a control group. The patients underwent EDX testing, and the severity of CTS was determined using Canterbury grading (6 grades). The patients were subsequently classified into nerve conduction study (NCS)-negative (normal NCS), mild-to-moderate CTS (grades 1–3), and severe CTS (grades 4–6).

Science News: Amyotrophic Lateral Sclerosis Mortality Rates in Latin America and the Caribbean: A Meta-Analysis

    7/13/2022
Heterogeneity of amyotrophic lateral sclerosis (ALS) epidemiology has been noted amongst geographic population. Previous studies have shown lower frequency of ALS amongst non Caucasian descents. Furthermore, interesting findings like lowest mortality from ALS in mixed ancestry has been noted. This study conducted a meta-analysis of population-based data to describe ALS mortality rates in Latin America.

Science News: A New Tool for Assessment of Motor Axon Excitability. A Multicenter Prospective Study

    7/8/2022
This study is a multicenter study that assessed a novel electrodiagnostic test, ‘iMAX’, to test the motor axon excitability. The study was performed in four centers in Belgium and France. The authors aimed to evaluate the test reliability and consistency among the four centers, provide normative values, and determine its ability to detect impaired motor axon excitability in patients with peripheral neuropathies. 

Science News: Dermatomyositis: Muscle Pathology According to Antibody Subtypes

    6/27/2022
Dermatoyositis (DM) is a rare disease that causes muscle weakness and skin rash. This study provides good evidence for a variety of DM subtypes and highlights the importance of looking at myxovirus resistant protein expression in muscle biopsies when evaluating inflammatory myopathies.

Science News: ALS in Finland: Major Genetic Variants and Clinical Characteristics of Patients With and Without the C9orf72 Hexanucleotide Repeat Expansion

    6/27/2022
In this cohort study, the authors analyzed the frequency of major genetic variants and clinical features of patient with amyotrophic lateral sclerosis (ALS) with or without C9orf72 repeat expansion. The article explains the correlation between ethnicity and genotype phenotype correlations. 

Science News: CIDP: Five New Things

    6/14/2022
Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is one of the most common autoimmune neuropathies. The disease is heterogeneous with atypical case and evolving immunomodulation therapy. There are several recent developments in CIDP. This article brings us five take-home points.

Science News: Electrodiagnostic Characteristics Suggestive of Muscle-Specific Kinase Myasthenia Gravis

    6/14/2022
The authors highlighted potentially distinguishing electrodiagnostic features in the patient with MuSK+MG, consisting of myotonic discharges and myopathic appearing motor unit potentials, which may help to expedite the workup. The presence of these changes may be correlated to alteration of sodium channels.