AANEM News Express

AANEM News Express

Science News: Individualized Immunoglobulin Therapy in Chronic Immune-Mediated Peripheral Neuropathies

10/2/2018
 
Submitted by Benn E. Smith, MD, News Science Editorial Board
Edited by Leigh Maria K. Ramos-Platt, MD, News Science Editorial Board


Allen JA, et al. Individualized immunoglobulin therapy in chronic immune-mediated peripheral neuropathies. J Peripher Nerv Syst 2018;00:1-10.

This is the written manuscript by Allen and colleagues (an international cohort of peripheral nerve experts) on IVIg therapy utilization immune-mediated peripheral neuropathy. This review is based on a symposium presented at the 2017 Peripheral Nerve Society meeting in Sitges, Spain. The review is well-structured, beginning with a clear presentation of IVIg immunology, biology and pharmacokinetics, followed by a cogent discussion of the well-known “wearing off” phenomenon and the finally a recommended algorithm to be used to adjust frequency and dose adjustments in individual patients with neuropathies for which IVIg is given. 

Comment: This practical review will be of keen interest to all in the readership of Muscle & Nerve who use IVIg for immune neuropathies.


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