Submitted by Benn E. Smith, MD, News Science Editorial Board
Edited by Leigh Maria K. Ramos-Platt, MD, News Science Editorial Board
Allen JA, et al. Individualized immunoglobulin therapy in chronic immune-mediated peripheral neuropathies
. J Peripher Nerv Syst
This is the written manuscript by Allen and colleagues (an international cohort of peripheral nerve experts) on IVIg therapy utilization immune-mediated peripheral neuropathy. This review is based on a symposium presented at the 2017 Peripheral Nerve Society meeting in Sitges, Spain. The review is well-structured, beginning with a clear presentation of IVIg immunology, biology and pharmacokinetics, followed by a cogent discussion of the well-known “wearing off” phenomenon and the finally a recommended algorithm to be used to adjust frequency and dose adjustments in individual patients with neuropathies for which IVIg is given.
This practical review will be of keen interest to all in the readership of Muscle & Nerve
who use IVIg for immune neuropathies.