I evaluated a 45-year-old mechanic with neck pain and was impressed that all of his median and ulnar sensory amplitudes were unexplainably low (all < 10 µV), with borderline-prolonged distal latencies. He had no clinical evidence of a polyneuropathy or mononeuropathy, and no medical conditions aside from neck pain. He was muscular with very large hands. I know that height and BMI adversely influence sensory measures, but I’m wondering if his large hands explain the low sensory response amplitudes?