Filter by Topic

Filter by Type

Annual Meeting Collection
Case Report
Case Study
EMG Interactive Training Tools
Ethics Vignettes
Journal Review
Lecture Series
Live Event
Performance in Practice
Real EMG Interactive Case Studies
Self Assessment
Technologist Checkpoint
Technologist Products
Workshop Handout

Product Details

Genetic Modifiers of Duchenne and Facioscapulohumeral Muscular Dystrophies

  • Journal Review by Rylie M. Hightower, BSN and Matthew S. Alexander, PhD

  • Free! (Member price)
  • Free! (Non-Member price)

Please login to add this item to your cart.

  • Language: English
  • Published: 12/1/2017
  • Description: Free CME for Members! Muscular dystrophy is defined as the progressive wasting of skeletal muscles that is caused by inherited or spontaneous genetic mutations. Next-generation sequencing has greatly improved the accuracy and speed of diagnosis for different types of muscular dystrophy. Advancements in depth of coverage, convenience, and overall reduced cost have led to the identification of genetic modifiers that are responsible for phenotypic variability in affected patients. These genetic modifiers have been postulated to explain key differences in disease phenotypes, including age of loss of ambulation, steroid responsiveness, and the presence or absence of cardiac defects in patients with the same form of muscular dystrophy. This review highlights recent findings on genetic modifiers of Duchenne and facioscapulohumeral muscular dystrophies based on animal and clinical studies. These genetic modifiers hold great promise to be developed into novel therapeutic targets for the treatment of muscular dystrophies. Muscle Nerve 57: 6-15, 2018.

    The AANEM designates this enduring material for a maximum of 2 AMA PRA Category 1 Credits TM. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Credit expires 12/1/2020.

    To obtain CME, click the Add to cart button and follow the instructions to fulfill the order. You will receive a link to the CME questions once you click the Continue to payment button.

Featured Products

2019 Online Coding Guide

2018 Annual Meeting Presentation Series - Neuromuscular Edition

2018 Annual Meeting Presentation Series - Self-Assessment Edition

2018 Electrodiagnostic Self-Assessment Exam Online






Find Your Dream Job